11. Hyalinised glomeruli

Last updated on March 11, 2019 at 19:26

Staining: HE

Organ: Kidney

Description:

Four typical signs can be seen:

  1. Most glomeruli contain globular eosinophilic structures. Some glomeruli are unaffected.
  2. The tubulointerstitium is infiltrated by RBCs, lymphocytes and plasma cells
  3. The tubules contain eosinophilic substance, making they look like the thyroid histologically. This process is called thyroidisation.
  4. Arteriolosclerosis of the vessels in the renal sinus

Diagnosis: Hyalinised glomeruli

Causes:

  • Diabetic nephropathy
  • Chronic pyelonephritis
  • Rapidly progressing glomerulonephritis
  • Glomerulonephritis

Theory:

Hyalinisation of the glomeruli is the morphology of
the end-stage kidney disease (chronic renal failure), which is often the end-result of the conditions mentioned above.

Despite the loss of many glomeruli some are still normal and functioning, so the kidney still produces some urine.

Password-protected images

These images are password-protected due to copyright concerns. Please verify with a password to unlock the content. If you are a medical student in Pécs or feel like you should have access to the content for any other reason, send me an e-mail.


Previous page:
10. Rapidly progressive GN with crescents

Next page:
12. Kimmelstiel Wilson syndrome

Leave a Reply

Only the "Comment" field must be filled in. It is not compulsory to fill out your name; you can remain anonymous. Do not fill out e-mail or website; if you do, your comment will not be published.