25. Subacute granulomatous thyreoiditis (De Quervain)

Staining: HE

Organ: Thyroid

Description:

Areas of normal thyroid is separated by fibrosis, causing the formation of “islands” of thyroid follicles. Also present are some giant cells, indicating that this is a granulomatous inflammation.

Diagnosis: Subacute granulomatous thyroiditis / de Quervain’s thyroiditis

Causes:

  • Viral infection, often upper respiratory tract

Theory:

This is a self-limiting disease that goes away after 6-8 weeks without treatment. Fibrosis is only present in the late stages of this condition, either right before or after remission. This indicates that this sample was taken from a patient who had late-stage subacute granulomatous thyroiditis. This also explains why there are so few giant cells present.

Password-protected images

These images are password-protected due to copyright concerns. Please verify with a password to unlock the content. If you are a medical student in Pécs or feel like you should have access to the content for any other reason, send me an e-mail.


Previous page:
24. Prion disease, spongioform encephalopathy

Next page:
26. Papillary carcinoma of the thyroid

Leave a Reply

Only the "Comment" field must be filled in. It is not compulsory to fill out your name; you can remain anonymous. Do not fill out e-mail or website; if you do, your comment will not be published.