13. Hypovolemic shock: Causes and hemodynamics

Last updated on May 24, 2019 at 17:12

Hypovolemic shock occurs when there is loss of more than 20 % of intravascular fluid volume. It can be caused by both hemorrhagic and non-hemorrhagic fluid loss.

Here are the most common causes:

  • Haemorrhagic fluid loss
    • Trauma
    • Surgery
    • Variceal bleeding
    • Postpartum bleeding
  • Non-haemorrhagic
    • Diarrhoea
    • Vomiting
    • Burns
    • Dehydration
    • Loss of fluid to “third spaces”
      • Fluid moving to peritoneal, pleural or pericardial cavity
      • Acute pancreatitis
      • Ileus
      • Ascites
Pathomechanism and compensation

The blood volume will decrease, leading to a decreased venous return. Due to this, every circulatory parameter that has something with the blood volume and pressure to do decreases, while heart rate, the resistance and the time of the circulation increases.

Blood volume
Venous return
Central venous pressure
End-diastolic volume and pressure
Stroke volume
Cardiac output
Arterial blood pressure
Heart rate
Total peripheral resistance
Circulatory time

To compensate this, as discussed in the previous topic, the sympathetic activation will lead to tachycardia and increased total peripheral resistance. It will also empty the blood stores and increase the retention of water and salt to try to regain the lost fluid.


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12. Definition and classification of circulatory shock. Pathophysiology of development, phases and characteristics of microcirculation

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14. Cardiogenic shock: Causes and hemodynamics

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