40. Paget disease

Page created on May 1, 2019. Last updated on May 14, 2019 at 20:28

Staining: HE

Organ: Nipple

Description:

The squamous cells of the epidermis are replaced by tumor cells showing significant atypia.

The actual tumor or DCIS is not visible on this slide.

Diagnosis: Paget disease of the breast

Causes:

  • Cancer cells invading the epidermis of the nipple

Theory:

Paget disease of the breast can occur both in DCIS and in invasive carcinoma. It can look like eczema.

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