|0||Carcinoma in situ|
|I||Tumour strictly confined to the cervix|
|Ia1||Stromal invasion < 3 mm in depth|
|Ia2||Stromal invasion 3 – 5 mm in depth|
|Ib||Stromal invasion > 5 mm in depth|
|II||Tumour invades beyond the uterus, but not into the pelvic wall or lower third of the vagina|
|III||Tumour invades pelvic wall and/or lower third of the vagina and/or causes hydronephrosis|
|IVa||Tumour invades adjacent organs|
(I’ve excluded some of the substages for simplicity)
Surgery is the mainstay of treatment of cervical cancer.
- Conisation or total/simple hysterectomy for stage Ia1
- Radical (Wertheim) hysterectomy up until and including stage IIa
Surgery is not the main treatment in stage IIb and beyond. However, it may be part of the adjuvant treatment.
Chemotherapy and radiotherapy
Radiotherapy may be used as primary therapy in early stages (I – IIa) in cases where surgery is not an option.
For stages IIb to IVa radiochemotherapy is the main treatment. Treatment for stage IVb is palliative and is mostly chemotherapy.
The standard chemotherapy regimen is cisplatin-based. Chemotherapy is rarely used alone in the treatment of cervical cancer; it’s almost always combined with radiotherapy.
B20. Endometrial cancer; FIGO classification and therapy
B22. Hydatiform mole; symptoms, types, endocrinology and therapy