12. Amyloidosis of the liver

Page created on October 10, 2018. Last updated on January 17, 2019 at 16:56

Staining: HE

Organ: Liver


We can identify the organ by looking for portal triads. In some parts of the slide we can see normal hepatocytes, however in some parts we can see an eosinophilic, homogenous, hyaline (glass-like) substance. Some hepatocytes have small cytoplasm, making them look atrophied.

Diagnosis: Amyloidosis of the liver


  • See macropreparation 12


The homogenous substance is comprised of amyloids.

The atrophied hepatocytes have atrophied because they’ve been compressed by the amyloid accumulation.

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