Page created on December 3, 2018. Last updated on January 17, 2019 at 17:19
Organ: Superficial temporal artery
Three cross-sections of an artery can be seen. The upper right one is the easiest to examine. We can see giant cells, epithelioid cells, lymphocytes and plasma cells. The lumen of the artery is really narrow and the internal elastic lamina is disrupted.
Diagnosis: Giant cell arteritis
- Older people
- Females more affected than males
Giant cell arteritis, or temporal arteritis (when it affects the temporal artery) is a granulomatous inflammation that affects large arteries. Characteristic for the disease is that only certain parts of the affected artery show the histological signs of inflammation. If a preparation was taken from one of these parts could a false negative diagnosis be made. Optimally should a longitudinal section of the artery be examined, or multiple cross-sections (which could be why we have three sections here).