24. Prion disease, spongioform encephalopathy

Page created on March 20, 2019. Not updated since.

Staining: HE

Organ: Brain


There is a small region of the grey matter where there are “holes” between neurons. Some vessels resemble these holes.

Diagnosis: Prion disease


  • Infection by prions


As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells.

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