24. Prion disease, spongioform encephalopathy

Staining: HE

Organ: Brain


There is a small region of the grey matter where there are “holes” between neurons. Some vessels resemble these holes.

Diagnosis: Prion disease


  • Infection by prions


As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells.

Password-protected images

These images are password-protected due to copyright concerns. Please verify with a password to unlock the content. If you are a medical student in Pécs or feel like you should have access to the content for any other reason, send me an e-mail.

Previous page:
23. Senile plaques and neurofibrillar degeneration

Next page:
25. Subacute granulomatous thyreoiditis (De Quervain)

Leave a Reply

Only the "Comment" field must be filled in. It is not compulsory to fill out your name; you can remain anonymous. Do not fill out e-mail or website; if you do, your comment will not be published.