40. Paget disease

Last updated on May 14, 2019 at 20:28

Staining: HE

Organ: Nipple


The squamous cells of the epidermis are replaced by tumor cells showing significant atypia.

The actual tumor or DCIS is not visible on this slide.

Diagnosis: Paget disease of the breast


  • Cancer cells invading the epidermis of the nipple


Paget disease of the breast can occur both in DCIS and in invasive carcinoma. It can look like eczema.

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39. Complex sclerosing lesion

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41. Invasive ductal carcinoma

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