17. CLL or SLL infiltration in lymph node

Staining: HE

Organ: Lymph node


It’s obvious that this is a lymph node, however the normal architecture is absent. The lymph node is filled by the tumor cells, which have destroyed the normal structure of the lymph node. The tumor cells themselves show only mild atypia/pleiomorphism. They resemble centrocytes and are therefore centrocytic or centrocytoid.

Diagnosis: Chronic lymphocytic leukaemia


  • Not well known


The most frequent adult leukaemia.

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16. Follicular lymphoma

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18. Diffuse large B-cell lymphoma (DLBCL)

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