Page created on January 7, 2022. Last updated on April 18, 2022 at 19:27
Flashcards for what was previously pharma 1 (topics are mostly the same but out of order): Anki here and cram here.
For what was previously pharma 2: Anki here and cram here.
NB: Topic 28 is missing because it didn’t exist when I had pharma. However, I’ve written a bit about fluids in Anaesthesia and intensive care topic 6.
After reordering the topic list, some topics refer to other topics by the wrong number. If you find one, please leave a comment so I can correct it.
Interesting fact you already know: many of the drugs mentioned in the lecture are not used anymore. You can use this website to look up the drugs which are registered in Hungary, and you’ll find that many of them aren’t registered anymore. Drugs not found on the register, or found with a “TT” status, are generally no longer available.
- Topics which are now ancient artifacts
- 1. Basic mechanisms of drug actions (examples of drug effects on receptors, ion channels, enzymes, carrier systems and effects mediated by physicochemical interactions)
- 2. Characterisation of agonist-receptor interaction. Occupancy, affinity, dose-response curve, potency, efficacy
- 3. Significance of signal transduction mechanisms in the effects of drugs. Tachyphylaxis and tolerance to drugs
- 4. Mechanisms of drug antagonisms
- 5. Transport of drugs across membranes
- 6. Absorption of drugs
- 7. Distribution of drugs
- 8. Biotransformation of drugs
- 9. Excretion of drugs
- 10. Pharmacokinetics: zero and first order elimination kinetics, elimination half-life, volume of distribution, clearance, maintenance dose, loading dose, oral bioavailability
- 11. Drug formulations. Prescription writing
- 12. Drug research and development
- 13. Cholinergic agonists and cholinesterase inhibitors
- 14. Muscarinic receptor antagonists
- 15. Neuromuscular blocking agents
- 16. Agents acting on the biosynthesis, storage, release and elimination of catecholamines
- 17. Adrenergic receptor agonists
- 18. Adrenergic receptor antagonists (alpha blockers and beta blockers)
- 19. Pharmacology of protein and peptide mediators, the purinergic system and nitric oxide
- 20. Calcium channel blockers
- 21. Drugs acting on the renin-angiotensin-aldosterone system
- 22. Diuretic drugs
- 23. Antiarrhythmic drugs
- 24. Drugs used to treat congestive heart failure
- 25. Antianginal drugs
- 26. Antihypertensive drugs
- 27. Drugs that increase regional blood flow. Drug treatment of obesity
- 29. Drugs used to treat hyperlipoproteinemias
- 30. Anticoagulants, antiplatelet drugs
- 31. Fibrinolytics, antifibrinolytics, hemostatic agents
- 32. Drugs affecting hematopoiesis
- 33. Histamine, antihistaminic drugs
- 34. Serotonin, serotonin receptor agonists and antagonists
- 35. Pharmacology of eicosanoids. Drugs acting on smooth muscle
- 36. Non-steroidal antiinflammatory drugs. Aspirin, paracetamol
- 37. Non-steroidal antiinflammatory drugs: Drugs other than aspirin or paracetamol. Drugs used to treat gout.
- 38. Antineoplastic drugs: Cytotoxic drugs
- 39. Antineoplastic drugs: Biological therapy
- 40. Immunosuppressants, immunomodulators, treatment of rheumatoid arthritis
- 41. Drugs used to treat bronchial asthma
- 42. Drug treatment of allergic rhinitis. Antitussives, expectorants and mucolytics